Anna B. Lowit is the recipient of the Society of Toxicology (SOT) Enhancement of Animal Welfare Award. Dr. Lowit received a MS and PhD in environmental toxicology from the University of Tennessee. Currently, she serves as a senior science advisor for the US Environmental Protection Agency (US EPA) in the Office of Pesticide Programs (OPP). She was elected co-chair of and represents the US EPA on the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), a permanent committee under the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM). The ICCVAM is a committee of representatives from 16 federal agencies that require, use, generate, or disseminate toxicological and safety testing information.
In her role at the US EPA, Dr. Lowit has led various important initiatives advancing the agency’s strategic vision to adopt 21st-century, human-relevant in vitro and in silico testing approaches. These approaches have led directly to the development and implementation of strategies and programs to improve risk assessments while reducing animal use in toxicity testing. Because of her commitment to the 3Rs (replacement, reduction, and refinement of animal use in scientific research), the US EPA OPP developed and implemented a transparent, stepwise process for evaluating and implementing alternative methods of testing for acute oral, dermal, and inhalation toxicity, as well as eye irritation and skin and eye sensitization.
An internationally recognized and well-respected expert in alternatives to animal testing, Dr. Lowit has served on numerous committees related to advancing the 3Rs, including the ILSI Health and Environmental Sciences Institute (HESI) committees on 21st-century risk assessment and non-animal test methods. She is committed to collaboration and encourages others to develop partnerships to effectuate change in furthering the science and implementing real change in policy.
Dr. Lowit has been an active member of the Society since 2005. She has served as a councilor for the Risk Assessment Specialty Section and regularly presents at the SOT Annual Meeting and ToxExpo on topics such as the application of the 3R principles of animal welfare to the testing of agrochemicals and the alternative approaches for skin sensitization testing.