Early-Life Factors and Cancer Development Later in Life


By Anthony Ndifor posted 05-13-2021 15:22


The National Cancer Institute (NCI) has released a Notice of Special Interest (NOSI) to stimulate research focused on the roles of early-life factors (maternal-paternal, in utero, birth and infancy, puberty, adolescence, and young adult years) in cancer development later in life.

This NOSI seeks to further support research on early-life factors and cancer development later in life.

Studies proposed in response to this NOSI should focus on human studies but may incorporate research using animal models, especially in elucidating mechanisms relevant in humans. Human studies can be new, but applicants are encouraged to take advantage of existing resources such as from case-control and prospective studies, including birth cohort studies, and existing databases to utilize data and biological specimens to test hypotheses.

NCI recognizes the needs to support research focused on early-life factors and cancer development in humans because this is an area of research that remains highly understudied but has the potential to be transformative in terms of cancer prevention and intervention strategies earlier in life as opposed to the current practice.

Key Dates:

Release Date: May 5, 2021

First Available Due Date: June 5, 2021

Expiration Date: March 8, 2024