The September 2024 issue of Toxicological Sciences includes a #ToxSpotlight article that highlights the effects of developmental exposure to arsenicals on stress-related disorders, while another #ToxSpotlight article explores the complex interaction between cell cycle, intracellular metabolism, and macrophage activation following ozone exposure.
- ToxSpotlight Article: “Effects of Developmental Exposure to Arsenic Species on Behavioral Stress Responses in Larval Zebrafish and Implications for Stress-Related Disorders” (free to read; topic category: environmental toxicology)
- ToxSpotlight Article: “Transcriptional Profiling of Lung Macrophages following Ozone Exposure in Mice Identifies Signaling Pathways Regulating Immunometabolic Activation” (free to read; topic category: immunotoxicology)
Other papers in the September 2024 issue (sorted by topic category) are:
Carcinogenesis
“Acute Particulate Hexavalent Chromium Exposure Induces DNA Double-Strand Breaks and Activates Homologous Recombination Repair in Rat Lung Tissue”
Computational Toxicology and Databases
“A Computational Framework to In Silico Screen for Drug-Induced Hepatocellular Toxicity”
Developmental and Reproductive Toxicology
“Prenatal Exposure to an Environmentally Relevant Phthalate Mixture Alters Serum Cytokine Levels and Inflammatory Markers in the F1 Mouse Ovary”
“Threshold for Increased Liver Weight Is Protective of Other Effects in Peromyscus Exposed to PFNA”
Environmental Toxicology
“Developmental PFOS Exposure Alters Lung Inflammation and Barrier Integrity in Juvenile Mice”
Exposure Sciences
“Altered Oxidative Stress and Antioxidant Biomarkers Concentrations in Pregnant Individuals Exposed to Oil and Gas Sites in Northeastern British Columbia”
Genetic and Epigenetic Toxicology
“Acute Exposure to Dihydroxyacetone Promotes Genotoxicity and Chromosomal Instability in Lung, Cardiac, and Liver Cell Models”
Molecular, Biochemical, and Systems Toxicology
“Perfluorooctanoic Acid Triggers Premature Ovarian Insufficiency by Impairing NAD1 Synthesis and Mitochondrial Function in Adult Zebrafish”
Regulatory Science, Risk Assessment, and Decision Making
“CarcSeq Detection of Lorcaserin-Induced Clonal Expansion of PIK3CA H1047R Mutants in Rat Mammary Tissue”
“In Vitro to In Vivo Extrapolation from 3D hiPSC-Derived Cardiac Microtissues and Physiologically Based Pharmacokinetic Modeling to Inform Next-Generation Arrhythmia Risk Assessment”
Remember that electronic access to ToxSci articles is a benefit for Full and Associate members—use your SOT credentials to log in and view ToxSci articles. Other membership types can request discounted access to ToxSci at any time.
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