Neurobiology: Focusing on Neurotoxicology and Neuro-degeneration

Hosted by: The Association of Scientists of Indian Origin Special Interest Group and Molecular and Systems Biology Specialty Section

Registration required for this free webinar. 

Arsenic exposure can harm the brain, particularly the hippocampus, which is crucial for learning and memory. Our study explored how arsenic affects two important cell signaling pathways—the Wnt/β-catenin pathway, which supports brain cell function, and the EGFR pathway, which helps with cell growth and survival. We found that arsenic disrupted both pathways over time, leading to brain cell damage. However, treatments targeting these pathways—such as Wnt inhibitors, EGFR activators, and specific proteins—helped restore brain cell health and improved memory function in mice. These findings suggest that protecting these pathways could be a potential strategy to counteract arsenic-related brain damage and improve cognitive function.

Speaker:

• Sanghamitra Bandyopadhyay, CSIR-Indian Institute of Toxicology Research

Registration required for this free webinar.