Upcoming SOT Component Groups Webinars: May 2018

Upcoming Webinars

The Society of Toxicology (SOT) Component Groups (Regional Chapters, Special Interest Groups, and Specialty Sections) and committees host webinars throughout the year. Webinars are an effective distance-learning method intended to impart scientific knowledge to members of their group as well as the SOT membership at large. These webinars are just one of the many benefits of SOT membership.

Upcoming webinars for May 2018 are listed below.

Mid-Atlantic Regional Chapter (MASOT):

Topic: Safety Assessment of Consumer Products

Date and Time: Tuesday, May 8, 2018, 12:00 pm–2:00 pm Eastern Time

Event address for attendees

The webinar will cover various methods of assessment for the safety of consumer products. The presenters represent government, industry, and academia and the aspects that affect each sector will be touched upon in their presentations. Methods used for assessment, government regulations, and requirements for assessment of consumer products and industry challenges associated with such assessment will be discussed.

Big Data and Artificial Intelligence: Revamping Safety Sciences for Consumer Products
Thomas Hartung, MD, PhD, Johns Hopkins University, CAAT

Assessing Potential Health Risks of Chemicals in Consumer Products
Michael A. Babich, PhD, Director, Division of Toxicology & Risk Assessment, Directorate for Health Sciences, US Consumer Product Safety Commission

The Science of Risk Assessment as it Applies to Cosmetic Products
Timothy Stakhiv, PhD, DABT, Manager, Product Safety Americas, L’Oreal USA, Clark, NJ

Registration is required.

 In Vitro and Alternative Methods Specialty Section (IVAMSS) and Medical Device and Combination Product Specialty Section (MDCPSS):

Topic: An In Vitro Skin Irritation Test for Detection of Irritant Activity in Medical Device Extracts

Date and Time: Wednesday, May 9, 2018, 11:00 am–12:00 pm Eastern Time

Event address for attendees 

Assessment of dermal irritation is an essential component of the safety evaluation of medical devices. Testing the irritant capacity of medical device extracts is currently performed by either topical or intradermal injection in rabbits. Attendees will learn about an international validation study that evaluated living human tissues as potential replacements for the rabbit irritation test. In the chemical industry, the RhE model as described in OECD Test Guideline 439 is used to identify irritant chemicals. Although the basic principles remain the same, for application in other domains, adaptation of the assay may be necessary. Therefore, the OECD 439 protocol was modified for testing of medical device extracts. This modified protocol was first evaluated to demonstrate the presence of spiked irritant chemicals added to medical device extracts to show the capability of the modified RhE test protocol to detect irritants in a complex extract mixture. The real proof of the test would be to detect irritants in extracts of medical devices or materials used in the production of medical devices. Therefore, specific polymer materials were prepared containing irritant chemicals within the polymer matrix. With these materials two RhE models, EpiDerm™ (MatTek, Inc.) and SkinEthicTM RHE (EpiSkin, SA) were evaluated in an international round robin study. The read-out endpoint was the same as in OECD 439, that being tissue viability by the MTT method; in addition, Interleukin 1a release was also considered. In order to enhance the impact and future implementation of the RhE assay for medical device safety testing, a broad range of stakeholders were encouraged to join the round robin. Participants included medical device companies, contract research organizations, and university and governmental laboratories. The results of the round robin study showed that RhE tissue models could detect the presence of strong skin irritants at low levels in dilute medical device polymer extracts. Consequently, the protocol will now be adapted and proposed as a new ISO 10993 standard for medical device irritation testing.

Registration is required.

Occupational and Public Health Specialty Section (OPHSS):

Topic: Career Opportunities for a Toxicologist in the Public Health Field

Date and Time: Tuesday, May 29, 2018, 12:00 pm–1:30 pm Eastern Time

Event address for attendees 

Are there any jobs in Public Health as a toxicologist? What do I do to make myself more marketable? Why should I care about Public Health anyway? If you are interested in these topics, this may be the webinar for you. Andy Maier PhD, CIH, DABT, from the University of Cincinnati College of Medicine and Joel Bercu, PhD, MPH, DABT, from Gilead Sciences will share their experiences in navigating a career in Public Health. A brief introduction will be provided and then a Question and Answer session will be designed for open dialogue with the speakers.

Registration is required.

Recent Stories
SOT Concludes a Successful 2020 Virtual Meeting

Engage with the 2020 Virtual ToxExpo

Reflections on the 2020 Virtual Undergraduate Education Program