An underlying theme of this 2018 Annual Meeting Scientific Session was that new discoveries in the molecular mechanisms of autophagy and mitochondrial maintenance can further enhance our understanding of how pharmaceuticals and toxicants act on mitochondria.
This Scientific Session during the 2018 Annual Meeting and ToxExpo provided a comprehensive overview of the various tools available to assess the potential of drug candidates to induce adverse cardiovascular events.
This 2018 CE course on lead optimization provided an extensive overview of the strategies and approaches leading from drug target selection to lead identification, optimization, and selection of clinical candidates for first-in-human studies.
During a workshop session titled "Systems Toxicology: The Final Goal of the Emerging New Approach Methods," I laughed, learned, and literally cried, as Thomas Hartung discussed his personal experiences and work with "mini-brains."
Mitochondria (MT) are organelles commonly referred to as the powerhouse of the cell due to the fact that their main function is to generate ATP to provide energy for cellular functions.