As the various online repositories of toxicological information accrue and high-throughput screening technology creates billions of data points as a matter of course, the problem of data analytics and interpretation looms large for toxicologists used to traditional toxicity studies.
The presenters during the 2018 “Reducing the Uncertainty of Read-Across Predictions by New Approach Methodologies: Application in Regulatory Human Risk Assessments” Session provided good reasons to abandon old risk assessment habits and embrace new approach methodologies (NAM).
A systematic review (SR) is a secondary research process (research on research) and is gaining popularity in regulatory space lately. This 2018 session focused on the systematic review process and evidence-based methodologies (Big “S” and Big “R”) in toxicology regulator decision making.
Chemical grouping is an important tool that helps researchers and regulators sort through the universe of chemicals to identify the safe, the unsafe, and the useful. The 2018 session in this topic focused on ways grouping chemicals can lead to new insights and more effective chemical selections.
Human health risk assessment is traditionally hazard driven, but in this Annual Meeting workshop, the speakers suggested a paradigm shift toward exposure-driven assessment.