Blogs

The May 2024 issue of Toxicological Sciences includes a Contemporary Review that comprehensively overviews all relevant aspects inherent to intestinal failure-associated liver disease. The issue also features an In-Depth Review about insights into the occurrence, identification, contamination status, exposure limits, and toxicity of new unregulated disinfection by-products (nitrosamine DBPs) in drinking water while a Forum article explores the rabbit as a model species for general toxicology studies. Additionally, #ToxSpotlight articles describe how pyrolysis gas chromatography and mass spectrometry are used to evaluate microplastics in human placental samples and how carbamazepine (CBZ) affects the zebrafish’s immune system.

• Contemporary Review: “Parenteral Nutrition-Associated Liver Injury: Clinical Relevance and Mechanistic Insights” (free to read)
• In-Depth Review: “A Critical Review of Advances in Tumor Metabolism Abnormalities Induced by Nitrosamine Disinfection Byproducts in Drinking Water” (free to read)
• Forum: “Exploring Rabbit as a Nonrodent Species for General Toxicology Studies”
• ToxSpotlight Article: “Quantitation and Identification of Microplastics Accumulation in Human Placental Specimens Using Pyrolysis Gas Chromatography Mass Spectrometry” (free to read; topic category: emerging technologies, methods, and models)
• ToxSpotlight Article: “Carbamazepine Transmits Immune Effect by Activation of Gut-Liver Axis and TLR Signaling Pathway from Parental Zebrafish to Offspring” (free to read; topic category: environmental toxicology)

Other papers in the May 2024 issue (sorted by topic category) are:

Biomarkers

“Evaluation of Organophosphorus Pesticide Tyrosine Adducts for Postmortem Change by Human Serum Albumin with Liquid Chromatography Quadrupole Orbitrap Mass Spectrometry”

Carcinogenesis

“A Whale of a Tale: Whale Cells Evade the Driving Mechanism for Hexavalent Chromium-Induced Chromosome Instability”

Developmental and Reproductive Toxicology

“Prenatal Prednisone Exposure Impacts Liver Development and Function in Fetal Mice and Its Characteristics”

Endocrine Toxicology

“Technical Evaluation and Standardization of the Human Thyroid Microtissue Assay”

Environmental Toxicology

“Chronic Exposure to BDE-47 Aggravates Acute Pancreatitis and Chronic Pancreatitis by Promoting Acinar Cell Apoptosis and Inflammation”

Molecular, Biochemical, and Systems Toxicology

“Quantitative Cross-Species Comparison of Serum Albumin Binding of Per- and Polyfluoroalkyl Substances from Five Structural Classes”

Nanotoxicology

“Single Pulmonary Nanopolystyrene Exposure in Late-Stage Pregnancy Dysregulates Maternal and Fetal Cardiovascular Function”

Remember that electronic access to ToxSci articles is a benefit for Full and Associate members—use your SOT credentials to log in and view ToxSci articles. Other membership types can request discounted access to ToxSci at any time.

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