ToxSci February 2024 Issue Available

By Laurie Haws posted 02-01-2024 04:11 PM


The February 2024 issue of Toxicological Sciences includes a Contemporary Review that will discuss how CRISPR insertion and deletion mutations are susceptible to compensation by transcriptional adaptation, alternative splicing, and rescue by maternally derived gene products. Additionally, #ToxSpotlight articles will discuss how cadmium exposure following early-life respiratory syncytial virus infection has a significant impact on subsequent inflammatory response and lung metabolism and how environmental factors interact with genetics in the development of autoimmunity and autoimmune disease.

Other papers in the February 2024 issue (sorted by topic category) are:

Computational Toxicology and Databases
Rat Deconvolution as Knowledge Miner for Immune Cell Trafficking from Toxicogenomics Databases(open access)

Developmental and Reproductive Toxicology
Fetoplacental Disposition and Toxicity of Cadmium in Mice Lacking the Bcrp Transporter

Mono-(2-ethylhexyl) Phthalate Reversibly Disrupts the Blood-Testis Barrier in Pubertal Rats(open access)

Emerging Technologies, Methods, and Models
Extracellular Vesicles Altered by a Per- and Polyfluoroalkyl Substance Mixture: In Vitro Dose-Dependent Release, Chemical Content, and Microrna Signatures Involved in Liver Health

Endocrine Toxicology
Toxicological Mechanisms and Potencies of Organophosphate Esters in KGN Human Ovarian Granulosa Cells as Revealed by High-Throughput Transcriptomics

Exposure Sciences
Investigating the Replacement of Carboxylates with Carboxamides to Modulate the Safety and Efficacy of Platinum(II) Thioether Cyanide Scavengers(open access)

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