ToxSci September 2023 Issue Available

By Laurie Haws posted 09-07-2023 16:01


The September 2023 issue of Toxicological Sciences includes ToxSpotlight articles on how exposure to a specific phthalate may tamper with the ovarian insulin-like growth factor 1 system, affecting the reproductive health of female mice, and on a new high-throughput assay that may provide an in vitro solution to studying structural cardiotoxicity. The issue also features an In-Depth Review that examines the taxonomic domain of applicability in a cross-species adverse outcome pathway network for thyroid hormone system disruption.


Other papers in the September 2023 issue (sorted by topic category) are:


Role of Nrf2 in 1,2-Dichloropropane-Induced Cell Proliferation and DNA Damage in the Mouse Liver

Developmental and Reproductive Toxicology

Prenatal Exposure to Diethylstilbestrol Has Long-Lasting, Transgenerational Impacts on Fertility and Reproductive Development(open access)

Environmental Toxicology

IL33-Mediated NPM1 Promotes Fibroblast-to-Myofibroblast Transition via ERK/AP-1 Signaling in Silica-Induced Pulmonary Fibrosis

Genetic and Epigenetic Toxicology

CircRNA hsa_circ_0000043 Acts as a miR-4492 Sponge to Promote Lung Cancer Progression via BDNF and STAT3 Expression Regulation in Anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide-Transformed 16HBE Cells


Machine Learning Reveals Common Transcriptomic Signatures across Rat Brain and Placenta Following Developmental Organophosphate Ester Exposure

Organ Specific Toxicology

Lead Exposure Suppresses the Wnt3a/β-catenin Signaling to Increase the Quiescence of Hematopoietic Stem Cells via Reducing the Expression of CD70 on Bone Marrow-Resident Macrophages

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