ToxSci October 2023 Issue Available

By Laurie Haws posted 10-12-2023 12:34


The October 2023 issue of Toxicological Sciences includes ToxSpotlight articles that explain how the Comparative Toxicogenomics Database explores the way environmental chemicals interact with genes and influence biological processes to affect human health and how γH2AX and Ki-67 may be able to classify genotoxic hepatocarcinogens (GHs) from non-GH chemicals. The issue also features a ToxPoint article that discusses what the authors view as inherent flaws in the data and study of Ramazzini Institute carcinogenicity studies of aspartame.


Other papers in the October 2023 issue (sorted by topic category) are:

Computational Toxicology and Databases

Comparison of In Silico, In Vitro, and In Vivo Toxicity Benchmarks Suggests a Role for ToxCast Data in Ecological Hazard Assessment

Developmental and Reproductive Toxicology

Antiepileptic Drugs Are Endocrine Disruptors for the Human Fetal Testis Ex Vivo

Exosome-Shuttled miR-126 Mediates Ethanol-Induced Disruption of Neural Crest Cell-Placode Cell Interaction by Targeting SDF1

Emerging Technologies, Methods, and Models

Human Cell–Based In Vitro Systems to Assess Respiratory Toxicity: A Case Study Using Silanes(open access)

Environmental Toxicology

Arsenic Disrupts Extracellular Vesicle-Mediated Signaling in Regenerating Myofibers


Deletion of IL-1β Exacerbates Acrylamide-Induced Neurotoxicity in Mice

Tbx2 Knockdown Alleviated Sevoflurane-Induced Cognitive Disorder and Neuron Damages in Aged Rats via Suppressing Oxidative Stress and Ferroptosis

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