Speakers in this Roundtable Session talked about the role of toxicology and toxicity testing in legislation and regulatory decisionmaking as well as the challenges that accompany the consideration of alternative test methods in a legislative framework. Panelists for this session included Daland Juberg, Linda Birnbaum, Melvin Andersen, Steven Bradbury, Martin Stephens and Thomas Hartung. A lively question and answer session followed. Use the comment option below to continue the discussion.