The Society of Toxicology (SOT) is pleased to announce a four-part colloquia series in food safety presented in conjunction with the US Food and Drug Administration (FDA) Center for Food Safety and Applied Nutrition (CFSAN) to present scientific training that is high-quality, cutting-edge, future-oriented toxicological science to provide a well-grounded foundation to inform the work of US FDA employees. These sessions also are open to the public to attend in person or via webcast. These colloquia are professional development opportunities with international experts to deepen knowledge of toxicology and facilitate discussion of emerging toxicology methods and not a public forum for discussion of toxicology regulatory issues.
The first session “Complexities in Evaluating Human Clinical and Observational Data for Ingredient Safety Assessment: Partially Hydrogenated Oils (PHOs) As a Case Study” will be Friday, November 7, 2014, from 8:15 am–1:00 pm in the Wiley Auditorium on the CFSAN campus in College Park, Maryland.
Registration is required for the onsite colloquium and for the webcast.
Onsite deadline: Monday, October 27 and Webcast deadline: Friday, November 7
Toxicological evidence is important in evaluating the health risks of food components and additives. The first colloquium will provide a state–of–the art review of methodological approaches used in toxicology studies using methods and data related to the investigation of Partially Hydrogenated Oils. Traditional controlled studies are difficult to conduct in humans although evidence can be brought together from epidemiological and other clinical studies. In addition, application of data obtained in animal studies has to be carefully evaluated for applicability for humans. Presentations by experts in the field will provide the scientific basis for understanding of current methods and of the science in this area.
The Chair of the Organizing Committee is James Pestka, Michigan State University, and the Chair for the first colloquium is Martin Ronis, University of Arkansas Children’s Nutrition Center.
Speakers include:
- Martijn Katan, VU University, Amsterdam, The Netherlands, Health Effects of PHOs and Trans Fatty Acids: Data from Clinical Trials
- Ingeborg Brouwer, VU University, Amsterdam, The Netherlands, Epidemiological Studies on Health Effects of PHOs: Strengths and Limitations of the Available Human Data
- Weihsueh Chiu, US EPA ORD, Washington, DC, Dose-Response Assessment Approaches to the Analysis of Non-cancer Health Effects: Current Practices, Advice from the National Academies, and 2014 WHO/IPCS Guidance
- Michael Dourson, TERA, Cincinnati, Ohio, Mode of Action and Dose-Response Evaluation of the Effect of Partially Hydrogenated Oils on LDL–Cholesterol
- DeAnn Liska, Biofortis Clinical Research, Addison, Illinois, who will join the other speakers in the moderated panel discussion that will conclude the colloquium.
For more information see the Colloquium webpage or contact Laura Apelt at or 703.438.3115. Ext 1602.