Scientists who are using animal models for medical research are urged to review the new American Veterinary Medical Association (AVMA) Guidelines for the Euthanasia of Animals. The Guidelines were pubished in the Federal Register and offered guidance as to how the 2013 AVMA Guidelines will be implemented. All grantees are expected to fully implement these guidelines by September 1, 2013. The National Institutes of Health (NIH) is soliciting public input about issues related to the new guidelines. Comments must be submitted to NIH by Friday, May 31, 2013. To submit comments go to the NIH website.