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Around the Interwebs—Week of June 15, 2014

By Michelle Werts posted 06-19-2014 01:38 PM

  

More toxicology research funding through the National Institue of Environmental Health Sciences (NIEHS) Superfund Research Program was announced this week, giving funding to another university research center with an SOT member at its head. Plus, we have some new research on ridding the body of air pollutants and on the drug doxorubicin.

SOT Member Research
2000px-Doxorubicin-2D-structure.svg.pngIn a recent clinical trial, John Groopman and Thomas Kensler found that drinking a mixture containing broccoli sprouts caused people to expel the carcinogen benzene at a higher rate than those not drinking the broccoli sprouts. This study, published in Cancer Prevention Research, points to a potential solution for reducing the long-term health risks of air pollution. The research results were also featured in Time.

In a new study of doxorubicin in Environmental and Molecular Mutagenesis, Mugimane G. Manjanatha, Wei Ding, and Rohan Kulkarni used a combination of the comet assay, flow-cytometric peripheral blood micronucleus test, and pathway-focused gene expression profiling to determine whether or not the drug is genotoxic. Through their research, they found evidence that doxorubicin may cause damage to the heart’s DNA.

SOT Members in the News
In a new FDA Voice blog post, William Slikker, Jr., describes the National Center for Toxicological Research’s efforts to build global partnerships to improve public health. He writes, “… it does take a global village to give regulatory scientists the tools they need to ensure that the exciting new technologies will translate into products that are safe, effective and will enhance your life." 

The UK Superfund Research Center, led by Bernhard Hennig, received at $12.2 million federal grant to study the health and environmental impacts of hazardous waste.

Science News

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