by Jeff Moffit and Ed Deere, Chairpersons of 2017 CE AM06
Reproductive safety issues are a more common occurrence in drug development than you might expect. When these come along, it’s not always easy to determine where to start or if there is even a path forward. Whether you presently have an issue or just want to be prepared when one inevitably pops up, consider attending the Society of Toxicology (SOT) 2017 Continuing Education (CE) course Reproductive Toxicity: Challenges and Practical Approaches to Determine Risk in Drug Development. The goal of this course is intended to provide an overview of reproductive biology, typical mechanisms of toxicity, and detail potential approaches to critically evaluate reproductive liabilities for risk/benefit in humans.
This course is intended for toxicologists who encounter reproductive toxicity in a drug development setting, but these tools and approaches are equally applicable to assessing consumer products or environmental chemicals. We’re going to cover typical reproductive toxicities in males and females, how to deal with small molecules or biologics, and even what in vitro methods can mechanistically address your findings. Several case studies will be presented to help underscore the sequential thought processes to manage these challenging cases. This course is a great introduction to reproductive toxicity and gives potential ways to advance your program by managing these reproductive liabilities. For information on the full 2017 CE Program, visit the SOT website.