An SOT 53rd Annual Meeting Poster Session focusing on Non-Pharmaceuticals: Safety Evaluation Approaches was held on Wednesday, March 26, 2014 at the Phoenix Convention Center. Highlights from this session are provided below.
SOT’s poster session on safety
evaluation approaches for non-pharmaceuticals included more than 40 posters presenting cutting-edge approaches for assessing the safety of cosmetics, indirect food additives, art materials, and dietary supplements from diverse perspectives, including academia, government, and research associations. Such methods include QSAR modeling, in silico approaches, and tiered screening approaches to assess hazards and/or risks from many types of non-pharmaceuticals.
Hyato Nishida from
Japan’s Shiseido Research Center presented a tiered framework to assess the phototoxicity of cosmetic ingredients using photochemical and photo-biological properties, including use of a UV/VIS spectral analysis, an ROS assay, and a 3T3 NRU PT assay (poster pictured on the top right).
Cal Baier-Anderson of the US Environmental Protection Agency Design for the Environment (DfE) presented a poster titled “Using Cluster Approaches to Assess the Safety of Chemicals Used in Consumer Products” featuring DfE’s using of ChemAce cluste
ring software to assess hazards, and exampled ChemAce’s use to assess fragrance raw materials such as allyl esters (poster pictured on the left).
US FDA’s recent post-market re-evaluation on the safety of Irganox 1076 in food contact applications was presented, and included an update exposure assessment (poster pictured on the bottom right).