Blogs

Despite the cancellation of the 2020 SOT Annual Meeting, much of the scientific content intended for presentation during the in-person meeting is being creatively shared online. 

Rutgers, The State University of New Jersey, hosted the Rutgers Virtual Pharmacology and Toxicology Conference 2020 to allow participants of the 2020 SOT Annual Meeting and 2020 American Society for Pharmacology and Experimental Therapeutics Annual Meeting to share science intended for these meetings as well as to recognize awardees and leadership. 

Similarly, the National Toxicology Program of the National Institute of Environmental Health Sciences centralized materials intended for the 2020 Annual Meeting on its “Presentations at SOT 2020” web page. This page organizes all National Institutes of Health–related activities that were to take place during the 2020 Annual Meeting, including references to Continuing Education (CE) courses, Scientific Sessions, and Poster Sessions.

Additional forms of media also are being employed to present this science. Alison Bernstein, PhD, Co-Chair of the Informational Session “Communicating Risk in a (Mis)information-Rich World,” transformed her presentation into a blog post available on the SciMoms blog. Dr. Bernstein also will be sharing information on communicating risk during the live SOT webinar of her Informational Session on June 4.

In addition to the 625+ ePosters that are available for viewing through May 31, 2020, on the 2020 ePoster Index PDF, Online Planner, SOT Event App, and online version of the app, poster presenters have shared their research on their own platforms to maximize the scope of this science:

• “Toxicants Associated with Spontaneous Abortion in the Comparative Toxicogenomics Database (CTD)”
• “Transcriptional Comparison of Liver Cells to Reveal Biological Networks and Pathways Differentially Regulated for Each In Vitro Liver Model Systems”
• “BioCelerate Nonclinical Protocol Harmonization Initiative”
• “Correlation of Electrophysiological Parameters with Behavioral Performance in an Animal Model Using Aluminum Exposures”
• “Microphysiological System for Studying Fatty Liver Disease and Its Impact on Drug-Induced Liver Injury”
• “High-Throughput Phenotypic Profiling (HTPP) to Discern Putative Mechanism of Action (MOA) for Environmental Chemicals”
• “Predicting Subchronic and Chronic Animal Toxicity from In Vitro High Content Imaging Data using PBTK and Machine Learning”
• “The Process and Challenges of Deriving Exposure-Based Limits for Toxicological Risk Assessment for Components and Impurities Present in Cell Therapy Products with Case Studies”
• “An Adverse Outcome Pathway for Renal Tumors in Male Rats through Chemical Induction of α2u-globulin (α2u) Nephropathy (α2u-N)”
• “The Incidence of Infusion Reactions Associated with Monoclonal Antibody Drugs Targeting the Epidermal Growth Factor Receptor in Metastatic Colorectal Cancer Patients: A Systematic Literature Review and Meta-Analysis of Patient and Study Characteristics”
• “Risk Assessment of Manganese Exposure for Pica Child: Application of PBPK Modeling”
• “Creating a Literature Database for Cannabidiol (CBD): Systematic Evidence Mapping”
• “Quantitative Integration of Dose-Response Data for Relative Potency Estimates of Dioxin-Like Chemicals”
• “Oral and Inhalation Bioaccessibility of Cobalt and Nickel in Metal Alloys: A Critical Consideration for Site-Specific Human Health Risk Assessments and Read Across”
• “Exposure to Environmentally Relevant Concentrations of Hexavalent Chromium Does Not Induce Ovarian Dysfunction in Mice”
• “Systematic Characterization of Hexavalent Chromium and Potential Female Reproductive Outcomes: Application of US EPA Critical Appraisal Tools and Stepwise Inclusion of Mechanistic Data”
• “Correlation of Electrophysiological Parameters with Behavioral Performance in an Animal Model Using Aluminum Exposures”
• “Translational QSAR Models to Support Identification of Safety Signals and Alerts during Clinical Evaluation of New Pharmaceuticals”
• “Zebrafish as Complementary Model for Drug Discovery and Chemical Prioritization: An Example of High‐Throughput Screening Method to Validate Teratogenic Effects”

And don’t forget about the SOT-hosted Scientific Sessions and Continuing Education courses being held through the end of June 2020. The full schedule is available on the SOT Annual Meeting website.