Submitted by Eva McLanahan, President, Biological Modeling Specialty Section
The Biological Modeling Specialty Section (BMSS) has invited scientists from GlaxoSmithKline to present their work, developed in collaboration with Simulations Plus, on a Transdermal Compartmental Absorption & Transit (TCAT™) PBPK model. The model allows better understanding of chemical penetration through the skin while accounting for the formulation characteristics, evaporation, and precipitation effects that influence dermal delivery. We look forward to your participation!
BMSS Webinar: Understanding Dermal Drug Disposition Using TCAT—A Novel PBPK Model
February 16, 11:00 am EST
Skin is the major organ in the human body with a highly complex barrier that serves as protection from the external environment. Predicting dermal and systemic exposures of drugs following topical application is especially challenging when considering the impact of formulations. Scientists from GlaxoSmithKline and Simulations Plus have collaborated to develop a mathematical model, Transdermal Compartmental Absorption & Transit (TCAT™) that allows better understanding of drug penetration through the skin while accounting for the formulation characteristics, evaporation, and precipitation effects that influence dermal delivery. The talk entitled "Understanding Dermal Drug Disposition Using TCAT—A Novel PBPK Model" will focus on details of the TCAT model and what it offers. Following the completion of the seminar there will be time for questions and answers.
Registration is required for this event.
Event number: 733 772 689
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Access code: 733 772 689