Non-SOT Sponsored Meeting: GTA Conference Focuses on Current Developments in Genetic Toxicology


By Kevin Merritt posted 07-16-2015 13:30


Submitted by Krista Dobo, Genetic Toxicology Association, Board of Directors Chair

Below is the report of a meeting that was sponsored by the Society of Toxicology (SOT) as consistent with the Society's mission and objectives. For additional information about Non-SOT Meeting funding, please visit the SOT website.


The 2015 Genetic Toxicology Association Meeting (GTA) held at the University of Delaware was a highly engaging conference, jam packed with great scientific presentations, opportunities to make new connections or catch up those already established, learn about relevant vendor products, and have some fun.  There were over 120 people from nine different countries in attendance. The main meeting was preceded on the afternoon of May 5 with a “hands on” Dose Response Modeling workshop that was facilitated by George Johnson (Swansea University) and John Wills (Health Canada). Workshop participants, with laptops in hand, were walked through the process of loading data into a number of dose response modeling software applications and provided with guidance on the interpretation of the output. 

On the morning of May 6, the GTA Annual Meeting was kicked off by the keynote speaker, Igor Pogribny, US Food and Drug Administration, National Center for Toxicological Research (FDA-NCTR), who gave a presentation regarding the role of epigenetic events in the carcinogenic process and how use of epigenetic biomarkers could improve the assessment of a chemical’s carcinogenic risk.  Over the next two days, there were five symposia and a mini workshop that focused on topics of  interest to the GTA membership, including OECD guidance, risk management case studies, cross industry perspectives on genetic toxicology testing , dose response modeling and quantitative risk assessment, and adverse outcomes pathways. 

The symposia were supported by national and international speakers from industry, regulatory agencies, and academia. Another highlight of this year’s meeting was the poster speed session, which was held immediately before the traditional poster session.  At the speed session, every individual who submitted a poster abstract was given 2 minutes to present highlights of the information in their poster. This was a great opportunity for everyone from first year students to seasoned professionals to present and generate interest in their poster. Overall, the 2015 meeting was very successful thanks to the efforts of many including the speakers, session  chairs, vendors, meeting sponsors, GTA board members, and volunteers.