This week, SOT members published research that may have implications for Parkinson’s disease, oral exposure to silver nanoparticles, and exposures to endocrine-disrupting chemicals.
SOT Member Research
In an effort to better understand the disruption of neurotransmitter vesicle dynamics—and implications for neurodegenerative diseases like Parkinson’s—Gary W. Miller and a research team overexpressed a brain protein known as vesicular monoamine transporter 2 in mice. These mice then exhibited an increase of dopamine intake to the neurotransmitters called synaptic vesicles. These results were published in PNAS.
New research from Mary D. Boudreau and colleagues at the US Food and Drug Administration National Center for Toxicological Research evaluates changes in intestinal-microbiota and intestinal-mucosal gene expression in Sprague-Dawley rats after oral exposure to silver nanoparticles. The Nanotoxicology paper found that oral exposure to silver nanoparticles alters the microbiota, as well as gut-associated immune response.
SOT Members in the News
Richard Judson took to the US Environmental Protection Agency’s (EPA) Greenversations blog to discuss two recent agency papers on endocrine–disrupting chemicals, as well as the US EPA’s use of high-throughput screening assays for faster, more efficient testing.
Science News
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