The National Academies of Sciences, Engineering, and Medicine will be holding a workshop December 10–11, 2018, on current state-of-the-art in performing systematic reviews of mechanistic data to support chemical assessments. This workshop will be held at the National Academy of Sciences Building, 2101 Constitution Ave., NW, Washington DC 20418.
Topic areas include the following:
- Approaches and tools to search and screen the literature for mechanistic data,
- Approaches to evaluating the validity of mechanistic studies,
- Methods for assimilating and using mechanistic information to support evidence synthesis and integration, and
- Practical experience with implementing systematic reviews of mechanistic evidence into human health assessments.
The objective of the workshop is to explore relevant strategies and tools that are being developed and used across the systematic review and risk assessment communities to assist the US Environmental Protection Agency with developing guidance on performing systematic reviews of mechanistic data to support the chemical assessments in its Integrated Risk Information System program. A poster session will accompany the workshop that will have examples demonstrating the application of systematic review approaches to mechanistic data. The abstract submission deadline is September 30, 2018. For more information, please refer to the workshop website.