Join us on Sunday, March 13, 2016, for a Continuing Education Afternoon Course! Keep your knowledge up-to-date in your field or learn new techniques with presentations by top experts.
To see more information and to register for a course, visit the SOT Annual Meeting website.
Afternoon (PM) Courses include:
PM08 (Advanced) Approaches to Investigate and Assess Risks Associated with Drug-Induced Liver Injury (DILI)—This course will discuss DILI hazards that can be used to identify a compound’s potential to cause DILI. A general overview and introduction of DILI will be provided, followed by a clinician’s perspective on DILI focusing on DILI presentation using examples of key withdrawals. Subsequent presentations will focus on established and emerging science on DILI hazard risks; this will include a presentation on the role of reactive metabolites (RM) and covalent binding in increasing risk for immune or nonimmune mediated DILI.
PM09 (Basic) Exploring Chemical Space in the New Toxicity Testing Paradigm: From Data Curation to Computational Simulations—Attendees enrolled in this course will learn about the availability of different tools and vast numbers of resources to help them triage in vitro efforts, rationalize mode-of-action information, screen chemicals in a virtual world, and understand the issues of domain of applicability in toxicological studies.
PM10 (Basic) Genetics and Population Variability in Chemical Toxicity: The What, the How, and So What?—This continuing education course is designed to review basics of genetics and demonstrate how appreciation for the role of genetic variability and novel experimental and in silico models can become key elements in human health assessments of chemicals. This course will be informative to the risk assessment practitioners and the toxicology research community and increase the scientific impact of the fundamental toxicology studies.
PM11 (Advanced) Human Health Risk Assessment: A Case Study Application of Principles—Unique to this course, students will be provided a risk assessment problem consisting of fundamental environmental contamination levels and original publications describing toxicity studies and will be asked to characterize the hazard, estimate exposures via soil and water, develop measures of toxic potency, and develop risk values for a hypothetical environmental contaminant.
PM12 (Basic) Unique Approaches to Safety Assessment of Gene, Cell, and Nucleic Acid-Based Therapies—This course will introduce the audience to each of these four general categories of advanced therapies, provide a regulatory perspective on these modalities, and highlight where the standard approaches for safety assessment either do not apply or require unique application.
PM13 (Basic) Zebrafish as a Tool in Toxicology and Drug Discovery Screening—The course will address critical questions on the status of this model in hazard identification and risk assessment for environmental toxicants including progress in the field, loopholes, and data-gaps; novel upcoming developments; and the impact of this model on toxicology research in the 21st century, as well as the impact on safety assessment of drugs.