Microplastics and nanoplastics (MPs & NPs) are a growing environmental and human health concern. These tiny plastic fragments are ubiquitous, contaminating our food, water, and air. While research is ongoing, the potential health risks of human exposure to MPs & NPs remain largely unknown. This interdisciplinary international symposium aims to convene leading scientists, policymakers, and stakeholders to address this critical issue. Our focus is on the characterization of microplastics and nanoplastics, methods of measurement, exposure pathways, mechanisms of MPs & NPs-induced toxicity, risk assessment, strategies for intervention and prevention, and the potential for translation from basic bench science to population studies, or public policy. Our objective is to foster coordination, exchange, and disseminate information and to explore MPs & NPs-induced health effects.