Mr David Umbaugh, BS, MS

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I am interested in leveraging single-cell transcriptomics to study liver injury and repair. By taking advantage of RNA-seq at a single hepatocyte resolution, in combination with computational approaches, we have established a robust methodology to accurately map individual hepatocytes within the liver lobule along the portal-central vein axis. This enables us to study how a particular subpopulation of hepatocytes respond to a toxicant anywhere along this zonation axis.
Member Since 2019