Do you enjoy writing, plan on attending the 2025 SOT Annual Meeting and ToxExpo , and want to share scientific insights with the SOT community? Volunteer as an SOT Reporter! What Is the SOT Reporter Program? The SOT Reporter program invites members to...
Reflecting on childhood lessons about computers in the 2000s, it was emphasized that communicating with a computer required specific knowledge of the grammar and syntax of elaborate coding languages. Two decades later, the margin between the languages of computers and humans is as narrow as ever...
We are on a next-generation chemical risk assessment (NGRA) adventure, where we are gradually breaking free from old-school toxicity testing and moving into the exciting world of new approach methodologies (NAMs)! Animal use is being swapped as much as possible for high-tech NAMs, including in...
Holger Behrsing of the Institute for In Vitro Sciences jump-started the 2024 SOT Continuing Education (CE) course “Use of New Approach Methodologies for the Assessment of Inhaled Substances” with an overview of respiratory toxicity 2D and 3D test systems, where tiered approaches such as 2D...
Next-Generation risk assessment (NGRA) is a prospective approach to assessing the possible hazards associated with chemicals and components. It uses new approach methodologies (NAMs) to explore metabolic behaviors, exposure, and bioactivity with the goal of gaining a thorough understanding for...
During the 2024 SOT Annual Meeting and ToxExpo, a Symposium Session titled “Looking through the Haze: Is the Picture Any Clearer on the Effects of Cannabis and Cannabis-Related Products on Reproduction & Development?” provided a platform for an in-depth exploration of the intricate landscape...
The intricate biological interactions between humans and their environments have long been a subject of concern. Our lives have become entwined with an ever-expanding array of chemical compounds. Yet, despite this pervasive exposure, our understanding of how these chemicals interact within our...
The microbiome, often considered to be “the second genome,” has become increasingly recognized as relevant to human health over recent years. The microbiome is composed of bacteria, archaea, fungi, and viruses. In the gastrointestinal tract, it contributes over 200-thousand unique genomes linked...
In the vast world of molecular biology, there is a class of genetic players known as long non-coding RNAs (lncRNAs). These molecules, typically spanning over 200 nucleotides in length, make up a huge part of our genome and differ from our traditional genes—they don’t make proteins. Despite this,...
The world’s population of ages 60 and older is projected to nearly double by the year 2050. This, along with the statistic that seven million people in the US live with dementia, is alarming. The Symposium Session “The State of the Science Linking Environmental Chemicals to Age-Related...
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