Blogs

The June 2023 issue of Toxicological Sciences includes a Forum article in which the authors provide an alternative viewpoint to a European Food Safety Authority draft scientific opinion that the most sensitive outcome category to bisphenol A exposure is the immune system. There also are #ToxSpotlight articles on the weight of evidence for cross-species conservation of androgen receptor–based biological activity and the association between air pollution exposure and human endogenous retrovirus methylation.

• Forum Article: “When the Weight of Evidence Does Not Weigh Enough: EFSA’s Draft Scientific Opinion on BPA” (free to read; topic category: forum)
• ToxSpotlight Article: “Weight of Evidence for Cross-Species Conservation of Androgen Receptor–Based Biological Activity” (free to read; topic category: endocrine toxicology)
• ToxSpotlight Article: “Air Pollution and Human Endogenous Retrovirus Methylation in the School Inner-City Asthma Intervention Study” (free to read; topic category: molecular, biochemical, and systems toxicology)

Other papers in the June 2023 issue (sorted by topic category) are:

Developmental and Reproductive Toxicology

• “Triazole Fungicides Induce Adipogenesis and Repress Osteoblastogenesis in Zebrafish”

Environmental Toxicology

• “Pulmonary Immune Response Regulation, Genotoxicity, and Metabolic Reprogramming by Menthol- and Tobacco-Flavored E-Cigarette Exposures in Mice”

Neurotoxicology

• “Exposure To Quasi-Ultrafine Particulate Matter Accelerates Memory Impairment and Alzheimer’s Disease-Like Neuropathology in the Appnl-G-F Knock-in Mouse Model”
• “Reducing Uncertainties in Quantitative Adverse Outcome Pathways by Analysis of Thyroid Hormone in the Neonatal Rat Brain”

Organ Specific Toxicology

• “Chronic Exposure to a Mixture of Phthalates Shifts the White and Brown Adipose Tissue Phenotypes in Female Mice”

Regulatory Science, Risk Assessment, and Decision Making

• “A Tiered Testing Strategy Based on In Vitro Phenotypic and Transcriptomic Data for Selecting Representative Petroleum Uvcbs for Toxicity Evaluation In Vivo”
• “Manganese Relative Oral Bioavailability in Electric Arc Furnace Steel Slag is Influenced by High Iron Content and Low Bioaccessibility” (open access)

Remember that electronic access to ToxSci articles is a benefit for Full and Associate members—use your SOT credentials to log in and view ToxSci articles. Other membership types can request discounted access to ToxSci at any time.

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