SOT and the US Food and Drug Administration Human Foods Program (US FDA HFP) cordially invite you to join us for our December 3, 2024, colloquium, “Emerging Concepts in Hazard Identification and Exposure Assessment of Per- and Polyfluoroalkyl Substances.” There is no charge for this webcast. The SOT FDA Colloquia are an update on toxicological science rather than a public forum for discussion of toxicology regulatory issues. The Co-Chairs of this session are Jessica Camacho, PhD, US FDA; and Jamie DeWitt, PhD, Oregon State University.
Overview
Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic compounds that have been used across myriad products and processes, including grease-, water-, and stain-repellant coatings on textiles, cookware, and food contact materials. As a result of their widespread use, PFAS are now found in nearly every environmental matrix evaluated, including human biological tissues and fluids. Although some subsets of PFAS have been well-studied with respect to their human health toxicological hazards and drinking water exposures, questions remain about the vast majority of PFAS. Most of the general population is exposed to PFAS through food, but PFAS in food, including the types of individual PFAS found within various foods and food products, and the potential toxicity of less well-studied PFAS found in food are emerging areas of research. An additional challenge of PFAS is communicating their toxicological hazards and potential health risks from various exposure pathways. This colloquium will address these important information gaps in PFAS science and provide an opportunity for discussion.
Schedule (all times US EST, UTC -5)
9:00 AM–9:10 AM
Welcome
Cynthia Rider, PhD, DABT, SOT Vice President, NIEHS-NTP, Research Triangle Park, NC
9:10 AM–9:30 AM
General Introduction and Overview of PFAS and the Need to Grow Emerging Concepts in Their Hazard Identification and Exposure Assessment
Jamie DeWitt, PhD, Oregon State University, Corvallis, OR
9:30 AM–10:15 AM
From Fields to Food: Uncovering Dietary Sources of PFAS
Noelle DeStefano, PhD, Eurofins, Raleigh, NC
10:15 AM–10:30 AM
Break
10:30 AM–11:15 AM
Methods for Assessing the Human Health Risks of Data-Poor PFAS Compounds
Penelope Rice, PhD, DABT, US FDA HFP, College Park, MD
11:15 AM–11:45 AM
The Use of ATSDR’s Toxicological Profile for Perfluoroalkyls to Communicate PFAS
Brittany Szafran, DVM, PhD, ATSDR, Chamblee, GA
11:45 AM–12:45 PM
Roundtable Discussion
Moderator: Jessica Camacho, PhD, US FDA, College Park, MD
All speakers
Previous Colloquia Recordings
The video and speaker slides for “Current State of the Science: Toxicology of Cannabidiol and Other Cannabinoids,” the colloquium held May 8, 2024, are available on the colloquium website, as are materials for the other 30 previous sessions.
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