Blogs

blog_1.jpg

Celebrating the 2025 Best Postdoctoral Publication Awardees

By Olawande Olagoke posted 20 days ago

  

The SOT Postdoctoral Assembly (PDA) Executive Board is pleased to announce the three recipients of the 2025 Best Postdoctoral Publication Award (BPPA)! The BPPA recognizes talented postdoctoral researchers who have recently published papers in the field of toxicology as a result of their work conducted during their postdoctoral research experience.

Thomas Jackson, PhD
US EPA

Paper Citation:
Jackson, Thomas W., Christy S. Lambright, Nicola Evans, Leah C. Wehmas, Denise K. MacMillan, Jacqueline Bangma, L. Earl Gray Jr., and Justin M. Conley. 2024. “Exploring Maternal and Developmental Toxicity of Perfluoroalkyl Ether Acids PFO4DA and PFO5DoA Using Hepatic Transcriptomics and Serum Metabolomics.” Science of the Total Environment  Volume 953 (September): 175978.
View abstract

His advisor, Justin Conley, PhD, says of this paper,Clearly PFAS is a high focal area of toxicology research, and this manuscript reports high-quality data on both novel compounds and using integrated analyses of cutting-edge, big-data streams.The data reported here provide a major contribution to identifying critically dysregulated genes in both maternal and fetal livers for further investigation, as well as maternal serum biomarkers that are novel, such as highly reduced tryptophan and tryptophan metabolite concentrations.

 

Katherine Roth, PhD
Wayne State University

Paper Citation:
Roth, Katherine, Zhao Yang, Manisha Agarwal, Johnna Birbeck, Judy Westrick, Todd Lydic, Katherine Gurdziel, and Michael C. Petriello. 2024. “Exposure of Ldlr-/- Mice to a PFAS Mixture and Outcomes Related to Circulating Lipids, Bile Acid Excretion, and the Intestinal Transporter ASBT.” Environmental Health Perspectives 132, no. 8 (August): 087007.
View abstract

Her advisor, Mike Petriello, PhD, says,We are very proud of this paper as it is the first Environmental Health Perspectives publication from our lab, and we think it implicates an understudied organ, the intestine, as a critical mediator of PFAS-induced increases in circulating bile acids and cholesterol. Katherine’s work was also important because most PFAS exposure studies in mice use wild-type mice that have high HDL levels, which is not entirely translatable to humans. Katherine’s mouse model has high VLDL/LDL cholesterol, which increases the translatability.

Jing Zheng, PhD
University of Calgary

Paper Citation:
Zheng, Jing, Dinara Baimoukhametova, Catherine Lebel, Jaideep S. Bains, and Deborah M. Kurrasch. 2024. “Hypothalamic Vasopressin Sex Differentiation Is Observed by Embryonic Day 15 in Mice and Is Disrupted by the Xenoestrogen Bisphenol A.” Proceedings of the National Academy of Sciences of the United States of America 121, no. 21 (May): e2313207121.
View abstract

His advisor, Deborah Kurrasch, PhD, states, There are two main takeaways from this paper: (1) Neural progenitors are sensitive to sex hormone disruptions at the earliest stages of development, leading to lasting effects on brain functioning, and (2) environmental levels of bisphenol A that match those reported in the human umbilical cord can interfere with these sex hormonesensitive neurodevelopmental programs. Although we and others have shown that bisphenol A can disrupt the timing and duration of neurogenesis, it was surprising to us that it could do so in a sexually dimorphic manner.

Congratulations to each of the awardees. These papers and the others submitted demonstrate the important research that is conducted during postdoctoral studies. The awards will be presented at the PDA Luncheon during the 2025 SOT Annual Meeting and ToxExpo in March. Each award recipient will receive $250 and a plaque recognizing their achievement.


#Awards
#Communique:SOTNews

0 comments
9 views