The SOT Postdoctoral Assembly (PDA) Executive Board is pleased to announce the three recipients of the 2025 Best Postdoctoral Publication Award (BPPA)! The BPPA recognizes talented postdoctoral researchers who have recently published papers in the field of toxicology as a result of their work conducted during their postdoctoral research experience.
Thomas Jackson, PhD
US EPA
Paper Citation:
Jackson, Thomas W., Christy S. Lambright, Nicola Evans, Leah C. Wehmas, Denise K. MacMillan, Jacqueline Bangma, L. Earl Gray Jr., and Justin M. Conley. 2024. “Exploring Maternal and Developmental Toxicity of Perfluoroalkyl Ether Acids PFO4DA and PFO5DoA Using Hepatic Transcriptomics and Serum Metabolomics.” Science of the Total Environment Volume 953 (September): 175978.
View abstract
His advisor, Justin Conley, PhD, says of this paper, “Clearly PFAS is a high focal area of toxicology research, and this manuscript reports high-quality data on both novel compounds and using integrated analyses of cutting-edge, big-data streams. … The data reported here provide a major contribution to identifying critically dysregulated genes in both maternal and fetal livers for further investigation, as well as maternal serum biomarkers that are novel, such as highly reduced tryptophan and tryptophan metabolite concentrations.”
His advisor, Deborah Kurrasch, PhD, states, “There are two main takeaways from this paper: (1) Neural progenitors are sensitive to sex hormone disruptions at the earliest stages of development, leading to lasting effects on brain functioning, and (2) environmental levels of bisphenol A that match those reported in the human umbilical cord can interfere with these sex hormone–sensitive neurodevelopmental programs. Although we and others have shown that bisphenol A can disrupt the timing and duration of neurogenesis, it was surprising to us that it could do so in a sexually dimorphic manner.”
Congratulations to each of the awardees. These papers and the others submitted demonstrate the important research that is conducted during postdoctoral studies. The awards will be presented at the PDA Luncheon during the 2025 SOT Annual Meeting and ToxExpo in March. Each award recipient will receive $250 and a plaque recognizing their achievement.
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