The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) requests the nomination of reference chemicals, with supporting data, to be used to validate in vitro metabolizing systems with the potential to interact with estrogen receptors (ERs) or androgen receptors (ARs). Specifically, reference chemicals are needed to characterize the usefulness and limitations of in vitro metabolizing systems for use in conjunction with ER and AR transactivation tests.
Details of the request were published in the Federal Register that is available on the NTP website. Additional information and an Excel template for data submission are available at the NTP website. Please submit nominations to NICEATM by June 2.