The Agust 2014 Vol. 140, Issue 2 of Toxicological Sciences is now available online. To have the email Table of Contents (eTOC) alerts delivered to you as well as Advance Access notification of the latest papers and research in Toxicological Sciences as soon as they are accepted and posted to the website, please register online.
The paper selected for the Editor's Highlight in this issue is Toxicogenomics in the 3T3-L1 Cell Line, a New Approach for Screening of Obesogenic Compounds by Anna Pereira–Fernandes, Caroline Vanparys, Lucia Vergauwen, Dries Knapen, Philippe Germaines Jorens, and Ronny Blust. The Editor's Highight by Toxicological Sciences Editor–in–Chief Gary W. Williams notes that "Obesity has reached epidemic proportions across the world, and with it come several serious health issues. Obesogens are chemicals proposed to disrupt lipid homeostasis and potentially promote the deposition of fat stores. The relative contribution of such chemicals to the overall problem of obesity is not clear, but it is a topic worthy of study. Initial studies have examined a limited number of suspected compounds. In this issue of Toxicological Sciences, Pereira–Fernandes et al. describe a transcriptomic screening approach using pre–adipocytes cells. While these results will need to be validated by in vivo studies, such high throughput strategies will be essential if we hope to test the thousands of chemicals to which we are exposed for their potential to alter energy homeostasis and body composition."
The mission of Toxicological Sciences. the official journal of the Society of Toxicology, is to publish the most influential research in the field of toxicology.