Dear SOT Member,
The September 2012, Vol. 129, No. 1 issue of Toxicological Sciences is now available online. To have the Email Table of Contents (eTOC) alerts delivered to you as well as Advance Access notification of the latest papers and research in Toxicological Sciences as soon as they are accepted and posted to the website, register online.
The paper chosen for the Editor's Highlight in this issue is Urinary Biomarker Detection of Melamine- and Cyanuric Acid-Induced Kidney Injury in Rats by Qin Zhang, Gonçalo Gamboa da Costa, Linda S. Von Tungeln, Cristina C. Jacob, Ronald P. Brown, and Peter L. Goering.
The Editor, Michael L. Cunningham, notes that "Melamine and cyanuric acid were added to pet food in the United States and baby formula in China to boost apparent protein content, resulting in widespread poisoning that was characterized by renal toxicity. The research conducted by the Goering group in this issue demonstrated that renal toxicity could be monitored by the analysis of urinary RPA-1 (distal tubule and collecting duct injury biomarker). This represents a novel and valuable biomarker for the noninvasive monitoring of obstructive nephropathy associated with melamine-cyanuric acid exposure."
Toxicological Sciences, the official journal of SOT, is among the most highly cited original research journals in Toxicology with an impact factor of 4.652.