The May 2013, Vol. 133, No. 1 issue of Toxicological Sciences is now available online. To have the email Table of Contents (eTOC) alerts delivered to you as well as Advance Access notification of the latest papers and research in Toxicological Sciences as soon as they are accepted and posted to the website, register online.
The paper chosen for the Editor's Highlight in this issue is
Biomarkers of Exposure and Effect in Human Lymphoblastoid TK6 Cells Following [13C2]-Acetaldehyde Exposure by Benjamin C. Moeller, Leslie Recio, Amanda Green, Wei Sun, Fred A. Wright, Wanda M. Bodnar, and James A. Swenberg
. ToxSci Associate Editor Jeffrey Fisher noted in his Editor's Highlight "Byproducts of constitutive metabolism may themselves be toxic, complicating the risk assessment of the same chemicals encountered from external sources. The application of stable labeled compounds offers insight into the source of chemicals producing biological effects and provides a basis to quantify the contribution of exogenous exposure to biological events. This report describes the concentration dependent contributions of exogenous [
13C
2]-acetaldehyde and endogenously produced acetaldehyde to adduct formation in human lymphoblastoid cells
in vitro."
Toxicological Sciences, the official journal of SOT, is among the most highly cited original research journals in Toxicology with an impact factor of 4.652.