The December 2014, Vol. 142, No. 2 issue of Toxicological Sciences (ToxSci) is now available online. To have the email Table of Contents (eTOC) alerts delivered to you as well as Advance Access notification of the latest papers and research in Toxicological Sciences as soon as they are accepted and posted to the website, register online.
In this month's Look Inside ToxSci, Editor-in-Chief Gary W. Miller notes that "It is truly a pleasure to read through the papers slated to appear in each month’s issue. Of course, deciding which articles to highlight continues to pose a problem, but what a great problem to have. Our authors have supplied the readers with a broad range of interesting topics, some of which are highlighted below. You will see excellent articles on safety evaluation of important therapeutics, evaluation of scorpion antivenoms, development of biomarkers of exposure, and toxicological effects of heavy metals and flame retardants. This issue also features a two-part Forum series that provides some insight into how adverse outcome pathway (AOP) models can be developed and implemented. I invite you to Look Inside ToxSci for the best original research in the field of toxicology."
The four highlighted papers in this issue are provided below.
Mitochondrial DNA Damage as a Peripheral Biomarker for Mitochondrial Toxin Exposure in Rats by Laurie H. Sanders, Evan H. Howlett, Jennifer McCoy, and J. Timothy Greenamyre
Glycodeoxycholic Acid Levels as Prognostic Biomarker in Acetaminophen-Induced Acute Liver Failure Patients by Benjamin L. Woolbright, Mitchell R. McGill, Vincent S. Staggs, Robert D. Winefield, Parviz Gholami, Mojtaba Olyaee, Matthew R. Sharpe, Steven C. Curry, William M. Lee, Hartmut Jaeschke, and the Acute Liver Failure Study Group
The Concordance between Nonclinical and Phase I Clinical Cardiovascular Assessment from a Cross-Company Data Sharing Initiative by Lorna Ewart, Mike Aylott, Mark Deurinck, Mike Engwall, David J. Gallacher, Helena Geys, Philip Jarvis, Haisong Ju, Derek Leishman, Louise Leong, Nick McMahon, Andy Mead, Phil Milliken, Willi Suter, Ard Teisman, Karel Van Ammel, Hugo M. Vargas, Rob Wallis, and Jean-Pierre Valentin
Prenatal Exposure to Polychlorinated Biphenyls and Their Hydroxylated Metabolites is Associated with Neurological Functioning in 3-Month-Old Infants by Sietske A. Berghuis, Shalini D. Soechitram, Pieter J.J. Sauer, and Arend F. Bos
The mission of ToxSci, the official journal of the Society of Toxicology, is to publish the most influential research in the field of toxicology.