Dr. John R. “Jack” Fowle III is the principal of Science to Inform, LLC, serving as an independent consultant advising clients on the use of science to inform decisions regarding environmental risk and in the development and use of alternatives for animal testing.
Prior to 2012, he was the Deputy Director of the U.S. Environmental Protection Agency’s (EPA) Health Effects Division in the Office of Pesticide Programs (OPP) in Washington, DC. He was responsible for directing the health risk assessment activities supporting the re-registration of existing pesticides as well as managed the integration of new toxicological approaches into OPP’s human health risk assessments. Before OPP, he was Director of EPA’s Neurotoxicology Division, as well as Assistant Laboratory Director, at the National Health and Environmental Effects Research Lab (NHEERL) in Research Triangle Park, NC helping to develop alternatives to animal approaches and to establish the Agency’s computational toxicology program. He has served as Deputy Director of EPA’s Science Advisory Board and as the Science Advisor to U.S. Senator Daniel Patrick Moynihan.
Since retiring from EPA, he serves on the Board of Directors for the Institute of In Vitro Sciences in Gaithersburg, MD, is President of the Board of Trustees for the Evidence Based Toxicology Collaboration at Johns Hopkins University and a member of the Board of Directors for the Center for Alternative Animal Testing also at Johns Hopkins University. He is President of the American Society for Cellular and Computational Toxicology as well as Past President of the Society of Toxicology’s In Vitro and Alternative Methods Specialty section. He received his baccalaureate and doctoral degrees in genetics from George Washington University in Washington, D.C. and he is a board certified toxicologist.