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Science On Demand: A Roundup of SOT Webinar Recordings Released July 1–September 30, 2023

By James Luyendyk posted 10-05-2023 13:13

  

Many of the webinars hosted by SOT Regional Chapters, Special Interest Groups, and Specialty Sections—collectively known as the SOT Component Groups—are recorded and added to the SOT Video Library so that SOT members and others can watch these valuable presentations at any time. SOT Committees, the Postdoctoral Assembly, and Graduate Student Leadership Committee also host webinars that are recorded. In this blog, you will find a listing of all the recent webinar recordings that have been added to the SOT Video Library.

 

2022 Drug Discovery Paper of the Year

Watch Webinar

Hosted by: SOT Drug Discovery Toxicology Specialty Section

Speaker: Tod Harper, PhD, DABT, Nonclinical Safety Scientist, Amgen

In this webinar, Dr. Tod Harper presents his award-winning research on an innovative bispecific T-cell engager and its associated toxicity in monkeys. His work has significant implications for the development of CD3 bispecific molecules, offering potential breakthroughs in drug discovery.

 

Advancements within the Field of Predictive Immunotoxicity In Vitro Models for Chemical Safety

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Hosted by: SOT In Vitro and Alternative Methods and Immunotoxicology Specialty Sections

Speakers:

  • George Papadopoulos, PhD, Investigative Toxicologist, Takeda Pharmaceuticals
  • Victor Johnson, PhD, Director of Operations, Burleson Research Technologies, Inc.

This webinar highlights the growing importance of predictive immunotoxicity assessment due to the increasing prevalence of drug-induced immune system disorders. Experts discuss their research on advanced in vitro assays, aiming to improve predictions of immunotoxicity liabilities in preclinical studies, ultimately enhancing drug safety.

 

Air Pollution and Pulmonary Fibrosis

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Hosted by: SOT Inhalation and Respiratory Specialty Section

Speakers:

  • Alessandro Venosa, PhD, Assistant Professor, University of Utah Department of Pharmacology and Toxicology
  • Jennifer Larson-Casey, PhD, Assistant Professor, University of Alabama at Birmingham Department of Medicine

This webinar explores the link between air pollution and pulmonary fibrosis. Dr. Venosa discusses immune cell heterogeneity during inflammation and lung remodeling, while Dr. Larson-Casey presents data on the role of immune responses in PM2.5-mediated exacerbations of pulmonary fibrosis, emphasizing the impact of air pollution on respiratory health.

 

A Clinically Focused and Integrated Look at the Impact of Wildfire on the Cardiovascular-Pulmonary Systems

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Hosted by: SOT Cardiovascular Toxicology and Inhalation and Respiratory Specialty Sections

Speakers:

  • Sanjay Rajagopalan, MD, Case Western Reserve University
  • Matt Campen, PhD, University of New Mexico
  • Mary Rice, MD, Beth Israel Deaconess Medical Center

This webinar addresses the alarming effects of wildfire-related air pollution on cardiovascular and pulmonary health. Experts discuss the growing risk posed by wildfires due to climate change and present clinical insights and novel approaches to understanding and mitigating the health impacts of wildfire smoke.

 

Computational Toxicology Top 3 Abstracts of 2023

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Hosted by: SOT Computational Toxicology Specialty Section

Speakers:

  • Kai Wang, PhD, Postdoctoral Fellow, University of Michigan
  • Isaac Mohar, PhD, Principal Toxicologist, Gradient
  • Mohan Rao, PhD, Toxicologist, Neurocrine Biosciences

Showcasing innovative research, this webinar features the top three abstract awardees of the Computational Toxicology Specialty Section in 2023. Topics include data fusion for exposome target interaction prediction, in silico toxicity screening of novel odorants, and computational analysis of discontinued neurological drugs, all highlighting the role of computational approaches in modern toxicology.

 

An Evaluation of the Occupational Hazards of Peptide Couplers

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Hosted by: SOT Occupational and Public Health Specialty Section

Speaker: Alejandra Trejo-Martin, MS, Senior Research Associate, Gilead Sciences

Peptide couplers, widely used in organic chemical syntheses, are the focus of this webinar. Alejandra Trejo-Martin discusses the occupational health hazards associated with these compounds, emphasizing dermal sensitization, corrosion, and irritation risks. The findings can contribute to safer chemical handling and hazard communication.

 

Mixture Toxicity in the 21st Century: Assessment Methods Presentations

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Hosted by: SOT Risk Assessment and Mixtures Specialty Sections

Speakers:

  • Kristin Eccles, PhD, Health Canada Healthy Environments and Consumer Safety Branch
  • Paul S. Price, PhD, Risk Sciences International, Inc.

This webinar delves into the challenges of assessing the risk of chemical mixtures, offering new approaches and methodologies. Topics include geospatial modeling of exposure to environmental chemical mixtures and the evolution of the Hazard Index as a tool for characterizing combined exposures to multiple chemicals.

 

Risk Assessment Syllabus: Basics of Exposure Assessment

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Hosted by: SOT Risk Assessment Specialty Section

Speakers:

  • Nicolle Tulve, PhD, US EPA
  • Dan Vallero, PhD, US EPA

This webinar provides a foundational understanding of human exposure assessment, covering key concepts such as intake, dose, and exposure routes. It aims to enhance the knowledge of risk assessment principles and their application in health evaluations.

 

ToxAIcology—The Future of Toxicology Is AI

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Hosted by: SOT Computational Toxicology Specialty Section

Speaker: Thomas Hartung, MD, PhD, Professor & Chair, Johns Hopkins University Bloomberg School of Public Health

Dr. Thomas Hartung discusses the evolving landscape of toxicology and the role of artificial intelligence (AI). He emphasizes the transformative potential of AI in exposomics, predictive toxicology, in vitro testing, digital pathology, and information extraction, paving the way for “Toxicology for the 21st Century 2.0.”

 

Update: The UK’s Medicines and Healthcare Products Regulatory Agency

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Hosted by: SOT Regulatory and Safety Evaluation Specialty Section

Speaker: David R. Jones, Retired, Expert Pharmacotoxicologist, Medicines and Healthcare Products Regulatory Agency

This webinar provides insights into the Medicines and Healthcare Products Regulatory Agency (MHRA) in the UK. David R. Jones discusses the role of the MHRA as an independent regulator, its divergence from the European Medicines Agency, and potential future developments post-Brexit.


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