The December 2025 issue of Toxicological Sciences includes an Editorial that highlights some recent adjustments made to Toxicological Sciences in an ever-changing publication landscape. One In-Depth Review highlights the current limitations and emerging opportunities in male reproductive in vitro models, providing a roadmap for integrating these systems into toxicology testing and drug development workflows, while another In-Depth Review evaluates key features of bone biology impacted by therapeutics and describes techniques for assessing bone toxicity during drug development. A Forum Article discusses the strategy of the ‘Omics for Assessing Signatures for Integrated Safety (OASIS) Consortium. Additionally, a #ToxSpotlight article explains how researchers created a diverse and strategically selected chemical library designed specifically for high-throughput toxicity testing within the PrecisionTox framework.
Other papers in the December 2025 issue (sorted by topic category) are:
Remember that electronic access to ToxSci articles is a benefit for Full and Associate members—use your SOT credentials to log in and view ToxSci articles. Other membership types can request discounted access to ToxSci at any time.
#ToxicologicalSciences