SOT FDA Colloquium April 8: The Toxicology of Nanoparticles


By Jia-Sheng Wang posted 02-11-2021 14:26


SOT and the US Food and Drug Administration Center for Food Safety and Applied Nutrition (US FDA/CFSAN) cordially invite you to join us for our April 8 colloquium, “The Toxicology of Nanoparticles.” There is no charge for this webcast. These colloquia are an update on toxicological science rather than a public forum for discussion of toxicology regulatory issues. The Co-Chairs for the colloquium are Rick Canady, NeutralScience, and Kapal Dewan, US FDA/CFSAN.

One of the most challenging aspects of safety assessment for nanomaterial use in consumer products is deriving an estimate of dose from use of a product that can be compared to doses delivered in a toxicology assay. What is the status of this critical translation between use and testing today? This SOT FDA Colloquium will explore issues of problem formulation for toxicology and exposure assessment in safety assessment of nanomaterial use in consumer products.

Schedule (All Times Are Eastern US, UTC -4)

9:00 AM–9:05 AM

George Daston, SOT President, Procter & Gamble Company, Mason, OH

9:05 AM–9:10 AM

Overview and Speaker Introductions
Rick Canady NeutralScience LC3, Camano Island, WA; and Kapal Dewan, US FDA/CFSAN, College Park, MD

9:10 AM–9:45 AM

Lessons Learned from Nanomaterial Characterization: Critical Quality Attributes That Influence Biological Properties
Anil Patri, NCTR, Jefferson, AK

9:45 AM–10:20 AM

Standard Dose Measurement for Nanomaterials: What to Include in Exposure and Toxicity so That We Can Bound Dose Estimates for Safety?
Christie M. Sayes, Baylor University, Waco, TX

10:20 AM–10:30 AM


10:30 AM–11:05 AM

Dosing-Related Challenges in Toxicity Studies and Risk Assessment of Titanium Dioxide in Food
Walter Brand, RIVM, Bilthoven, The Netherlands

11:05 AM–11:40 AM

Practical Application to Regulatory Toxicology: Issues Faced in Consideration of Developing Health Guideline Values
Lynne Haber, University of Cincinnati Risk Science Center, Cincinnati, OH

11:40 AM–12:40 PM

Roundtable Discussion
Moderator: Rick Canady, NeutralScience LC3, Camano Island, WA
Kapal Dewan, US FDA/CFSAN, College Park, MD
All speakers
Timothy Duncan, US FDA, Bedford, IL
Agnes Oomen, RIVM, Bilthoven, The Netherlands

Questions concerning the regulatory science for the roundtable discussion are encouraged from webcast participants. Regulatory policy will not be discussed.

The SOT FDA Colloquia on Emerging Toxicological Science: Challenges in Food and Ingredient Safety present scientific training that is high-quality, cutting-edge, future-oriented toxicological science for US FDA employees and the public.

Recordings and slides from the previous colloquia are available for free on the “SOT FDA Colloquia” web page, including the December 3, 2020, session, “New Plant-Based Foods and Proteins from Novel Sources.”