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Efforts Underway to Mine Big Data for Better Safety Assessments

Safety assessments are important. The process of evaluating human, animal, and environmental toxicity data is crucial for regulators, researchers, and companies that sell chemicals or biologics. The speakers for the 2018 Annual Meeting and ToxExpo Symposium Session “Application of Data from New...

Blog Entry
Read-Across Uncertainties in Risk Assessments: NAM to the Rescue!

For those of us in the risk assessment arena, deriving health reference values with a classic animal-based approach is part skill and part habit, honed by years of scouring in vivo studies to identify critical health effect endpoints, executing dosimetric conversions to deduce human equivalent...

Blog Entry
Using Chemical Grouping for More Effective Chemical Selection and Assessment

Chemical grouping is an important tool that helps researchers and regulators sort through the universe of chemicals to identify the safe, the unsafe, and the useful. The “Chemical Grouping for 21st-Century Toxicology, Risk Assessment, and Decision Making” session during the 2018 Annual Meeting...

Blog Entry
Use of Systematic Review to Support Regulatory Decision-Making

A systematic review (SR) is a secondary research process (research on research) and is gaining popularity in regulatory space lately. The 2018 SOT Annual Meeting and ToxExpo Informational Session “Moving Beyond Theory to the Use of Systematic Review to Support Regulatory Decision Making for...

Blog Entry
Bridging Exposure Science into Future Human Health Risk Assessment

Human health risk assessment has four critical components: hazard identification, exposure assessment, dose-response assessment, and risk characterization. However, human health risk assessment is traditionally hazard driven because the exposure data is limited at the initial stage and usually...

Blog Entry
Upcoming Component Group Webinars for November 2017

The Society of Toxicology (SOT) Component Groups (Regional Chapters, Special Interest Groups, and Specialty Sections) host many webinars throughout the year. Webinars are an effective distance-learning method intended to impart scientific knowledge to members of their group as well as the SOT...

Blog Entry
Advances in Read-Across and Challenges Yet to Be Overcome

The following blog pertains to the 2017 SOT Annual Meeting Scientific Session "Opportunities for Read-Across Development and Application Using QSAR Approaches." As recently as 25 years ago, applying read-across techniques to predict the toxicity of a target chemical was rare. Trailblazers in...

Blog Entry
Updates on Freely Available Data Sources to Aid in the Creating Safer Consumer Products

The following blog pertains to the 2017 SOT Annual Meeting Scientific Session "Measurement and Prediction of Chemicals in Consumer Products." Not to be thwarted by the week’s surprise snowstorm in Baltimore, toxicologists were back in force at SOT to attend a workshop session that presented...

Blog Entry
Data Is the Currency of Science, But When Will It Be Open?

The following blog pertains to the 2017 SOT Annual Meeting Scientific Session "Supporting Open Data in Toxicology." Data is the currency of science, and everyone, from toxicologists to tech companies always seem to need more of it. But how do we make the most of the data that we have? And how...