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Have you ever wondered how climate change affects the air you breathe? Would you believe that a role played by Nicolas Cage could spark a career in toxicology? This year’s InTOXicating Science Talks tackle two very different lines of inquiry, with interesting results! In “ Inhalation Toxicology in the Era of Climate Change ,” SOT Postdoctoral member Faria Khan, PhD, Harvard University T.H. Chan School of Public Health, explores how harmful toxins in the air impact organisms in the current era of environmental transformation. Watch video >> In “ What Inspires a Career in Toxicology? A Nicolas Cage Story ,” SOT Vice President–Elect Jim Luyendyk, ...
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This blog was authored by 2023 SOT Diversity Initiatives Career Development Award recipient Jada Spady, and I am pleased to share it on her behalf. Thanks to the support of the 2023 SOT Diversity Initiatives Career Development Award , I had the opportunity to complete a summer internship at Genentech in South San Francisco, California, as a Clinical Pharmacology Intern! Genentech is a leading biotechnology company that recently became renowned for its breakthroughs in recombinant DNA, allowing for the creation of genetically engineered drugs and the production of human proteins. For 12 weeks, I was able to work with some of the brightest minds in the industry ...
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This blog was prepared by and is being shared on behalf of the Safety Pharmacology Society (SPS) as part of a blog exchange between SPS and SOT. Are you ready to be at the forefront of safety pharmacology advancements? Join the Safety Pharmacology Society (SPS) at the 2024 SPS Annual Meeting in San Diego! Dates: September 22–25, 2024 Location: Town and Country Resort, San Diego, CA Topics/Sessions: Keynote Address: Artificial Intelligence Will Only Replace Safety Pharmacologists, Who Don’t Use It! Advancing 3Rs in Safety Pharmacology Innovative Technologies with Application to Safety Pharmacology ...
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Whether you’re diving into new topics, refreshing your memory on familiar ones, or fulfilling your continuing education (CE) credit hour requirements, the SOT CEd-Tox library is your go-to solution. With an expansive selection of over 100 courses spanning the entire spectrum of toxicology, your learning journey is always just a click away—whenever you need it! But wait, there's more! We're thrilled to announce that thirteen new CE courses, originally presented and recorded during the 2024 SOT Annual Meeting and ToxExpo, have been added to the CEd-Tox course library ! The 2024 courses cover topics such as cell and gene therapy, metal toxicity and aging, ...
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Reflecting on childhood lessons about computers in the 2000s, it was emphasized that communicating with a computer required specific knowledge of the grammar and syntax of elaborate coding languages. Two decades later, the margin between the languages of computers and humans is as narrow as ever. When I found out about the release of ChatGPT, a type of artificial intelligence (AI) known as a large language model, I was ecstatic about trying this technology for myself. I spent hours “conversing” with ChatGPT about biology, practicing my German, and even had it write some silly haikus. While scanning potential sessions to attend at the 2024 SOT Annual Meeting ...
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We are on a next-generation chemical risk assessment (NGRA) adventure, where we are gradually breaking free from old-school toxicity testing and moving into the exciting world of new approach methodologies (NAMs)! Animal use is being swapped as much as possible for high-tech NAMs, including in-vitro screening to assess chemical risks faster than ever before. In vitro – in vivo extrapolation (IVIVE) is a technique we are using to close the gap between laboratory research and real-world scenarios. By utilizing high-throughput toxicokinetic (HTTK) techniques, we are accelerating our toxicokinetic data processing beyond our past capabilities. HTTK is helping ...
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Holger Behrsing of the Institute for In Vitro Sciences jump-started the 2024 SOT Continuing Education (CE) course “Use of New Approach Methodologies for the Assessment of Inhaled Substances” with an overview of respiratory toxicity 2D and 3D test systems, where tiered approaches such as 2D pulmonary cell cultures are first used to screen respiratory toxicants and then followed by more complex 3D systems such as reconstituted human airways. His presentation underscores the importance of working with an experienced laboratory to select relevant test systems. Next, Shaun McCullough of RTI International identified many of the challenges associated ...
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Next-Generation risk assessment (NGRA) is a prospective approach to assessing the possible hazards associated with chemicals and components. It uses new approach methodologies (NAMs) to explore metabolic behaviors, exposure, and bioactivity with the goal of gaining a thorough understanding for applications. NGRA is based on an integrated strategy that combines chemical-specific data with computational and in vitro approaches. But it Is acknowledged that more NGRA education is needed, especially when it comes to choosing information sources and critically analyzing data to make decisions. Regulatory agencies are examining many case studies to confirm the effectiveness ...
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SOT is pleased to announce the five recipients of the 2024 Diversity Initiatives Endowment Career Development Award: Chamia Chatman, Endia Fletcher, Idoia Meaza, Samantha Serna, and Madeline Vera-Colón. The Diversity Initiatives Endowment Career Development Award enables undergraduate and graduate students to engage in education and career development opportunities with the aim of facilitating successful entry into advanced degree programs and transition into the modern toxicology workforce. This award supports activities that are outside of a student’s current program or institution. The SOT Diversity Initiatives Endowment Fund supports this award. Created in ...
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I would like to extend heartfelt gratitude to all members of the 2023–2024 SOT Council, as well as those dedicated individuals serving on our Elected and Appointed Committees and leading the SOT Regional Chapters, Special Interest Groups, and Specialty Sections. Your hard work and commitment have been instrumental in making the past year a resounding success. SOT Council tackled a big task this year in developing the Strategic Plan that will guide our Society for the next three years, and I believe that the result will serve as a great framework in the coming years. Thank you to all the SOT members that contributed to the strategic planning process through ...
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On May 30, applications will close for the first Mehendale Welcome Award, which will financially assist newly enrolled international graduate students in a biomedical scientific research program, with preference to those enrolled in a toxicology program, while they are adjusting to a new country (e.g., US). Rekha and Harihara Mehendale, for whom this award is named, were known for offering “a home away from home” to their students. As Dr. Mehendale’s final and only student at that time, I had the privilege of spending extensive time with him, from our initial email exchange in 2008 to our final interaction in 2022. Dr. Mehendale’s meticulous screening ...
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The May 2024 issue of Toxicological Sciences includes a Contemporary Review that comprehensively overviews all relevant aspects inherent to intestinal failure-associated liver disease. The issue also features an In-Depth Review about insights into the occurrence, identification, contamination status, exposure limits, and toxicity of new unregulated disinfection by-products (nitrosamine DBPs) in drinking water while a Forum article explores the rabbit as a model species for general toxicology studies. Additionally, #ToxSpotlight articles describe how pyrolysis gas chromatography and mass spectrometry are used to evaluate microplastics in human placental samples ...
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The 2024 SOT Annual Meeting and ToxExpo was chockful of exciting science and networking opportunities. The SOT Postdoctoral Assembly (PDA), for which I serve as Executive Board Chair, organized a slate of events to provide unique events especially tailored to the interests and needs of trainees. PDA Vice Chair Olawande Olagoke and I hosted a Tiny Tox Talk titled “We Have to Talk: Dealing with Difficult Conversations as a Postdoc.” The Tiny Tox Theater set-up allowed for an interactive and dynamic conversation with the audience. 2024 PDA Luncheon in Salt Lake City, Utah The PDA Luncheon on Tuesday offered an opportunity for postdocs at the meeting ...
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This blog was prepared by and is being shared on behalf of the Society of Environmental Toxicology and Chemistry (SETAC) as part of a blog exchange between SETAC and SOT. SETAC extends a warm invitation to members from SOT to attend the SETAC North America 45th Annual Meeting, which will be held from October 20–24, 2024, in Fort Worth, Texas. The meeting has a robust scientific program containing a variety of sessions. The meeting will span five days and includes 10 parallel oral sessions a day, poster sessions, plenty of engaging networking opportunities, and much more. More than 2,000 participants are expected from academia, business, government, ...
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Each month, SOT provides an update on activities and events of importance to the toxicology community through the release of the “Around the World of Toxicology” blog. To submit an event, opportunity, or information for consideration for inclusion in the monthly “Around the World of Toxicology” blog, complete the special submission form for “Around the World of Toxicology” items . Please note that only activities by societies and professional associations (i.e., nonprofits) will be considered. If you are an organization or company seeking to promote an event, please submit your activity to the SOT “ Calendar of Events .” Activity Announcements, Updates, ...
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SOT is pleased to announce the four newly elected members of the SOT Nominating Committee: Emanuela Corsini, PhD; Kembra L. Howdeshell, PhD; Marianna Stamou, PhD, DABT, and Courtney E. W. Sulentic, PhD. The Nominating Committee is charged with submitting nominations for each SOT elective office and Committee. Emanuela Corsini Dr. Corsini is Professor of toxicology at the School of Pharmacy at the Università degli Studi di Milano. She is active in training undergraduate and graduate students and in research. Her research focuses on the refinement of alternative in vitro tests for immunotoxicity and on the understanding at the molecular level ...
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SOT member Silvia Berlanga de Moraes Barros, PharmD, PhD, received the 2024 International Union of Toxicology (IUTOX) Lifetime Achievement Award during the IUTOX-supported 12th Congress of Toxicology in Developing Countries (CTDC) last week. Dr. Barros was nominated for this award by SOT and the Spanish Association of Toxicology (AETOX). A special thank you goes to the SOT Hispanic Organization of Toxicologists (HOT) Special Interest Group for recommending Dr. Barros to SOT Council and assisting with the nomination letter. To quote from the SOT nomination letter, “Professor Silvia Barros is a role model for the younger generation of toxicologists in Brazil ...
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During its meeting in January 2024, SOT Council met with Visit Orlando to discuss concerns expressed by SOT members about how safe attendees of the 64th Annual Meeting and ToxExpo will be based on Florida legislative actions in recent years. Council felt that it was extremely helpful to be able to discuss these topics directly with Visit Orlando and receive more detailed information about the state of affairs in the city. As a result, Council is giving this opportunity to the SOT membership by hosting a webinar on April 30 at 1:00 pm (US EDT, UTC -4) featuring guests from Visit Orlando to address any questions or concerns of SOT leaders and members. You ...
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When considering which Scientific Session and Continuing Education course proposals to accept for the SOT Annual Meeting and ToxExpo, endorsement of the proposal is an important factor. These endorsements can come from SOT Component Groups as well as SOT Committees. For example, Roundtables and Education-Career Development Sessions are often endorsed by Special Interest Groups and Committees as opposed to Specialty Sections. To make sure proposals are as strong as they can be, many endorsing groups will pre-review session proposals to provide feedback that can be incorporated into a proposal before it is officially submitted to the SPC by the May 15 deadline. ...
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Dr. Olawande Olagoke at the 2024 NPA Annual Conference As the airliner descended into the Seattle skyline, the picturesque background of the popular medical TV show set in the Emerald City came to mind. Luckily, it wasn’t pouring rain, so the Space Needle stood out among the architectural marvels between Lake Washington and Elliot Bay. Shortly before Grey’s Anatomy played its role in cementing Seattle on the pop-culture map, a committee of postdoc reps across America came together at the Science’s NextWave Postdoc Network in Washington, DC, in 2002 with the goal of “improving the postdoctoral experience.” The National Postdoctoral Association (NPA) was ...
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