The May 2023 issue of Toxicological Sciences includes ToxSpotlight articles on profiling mechanisms that drive acute oral toxicity in mammals and its prediction via machine learning and how vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to...
The April 2023 issue of Toxicological Sciences includes a contemporary review that examines glyphosate toxicity from an in vivo , in vitro , and epidemiological perspective and ToxSpotlight articles on how developmental exposure to an AHR-binding chemical can diminish methylation...
The March 2023 issue of Toxicological Sciences includes an editorial on the 2021–2022 ToxSci Paper of the Year recipient and honorable mention and ToxSpotlight articles on how arsenic causes distinct gene expression changes in macrophages polarized in vitro with either interferon-γ or...
In the February 2023 issue of Toxicological Sciences , a Contemporary Review examines manganese-induced neuronal apoptosis. The issue also includes ToxSpotlight articles on how cryopreserved human precision-cut lung slices can be a relevant model for use in regulatory applications and how...
During the SOT Awards Ceremony in Nashville, the recipients of the Toxicological Sciences Paper of the Year Award will be honored. Selected by the SOT Board of Publications, this award recognizes the author(s) of a paper published in the official SOT journal, Toxicological Sciences ,...
In the January 2023 issue of Toxicological Sciences , a Contemporary Review examines machine learning and artificial intelligence in physiologically based pharmacokinetic modeling. Other featured publications include #ToxSpotlight articles on how mild allergic airways responses to an...
In the December 2022 issue of Toxicological Sciences ( ToxSci ), the official journal of the Society of Toxicology (SOT), a Contemporary Review article examines the use of human-induced pluripotent stem cell–derived cardiomyocytes as a relevant assay for determining cardiac safety for...
To better understand the mass poisonings from pharmaceuticals to which diethylene glycol was mistakenly added, toxicologists examined how the metabolite diglycolic acid accumulates in kidney cells and specifically what role, if any, sodium dicarboxylate transporters play. The results of that...
In the newly released October 2022 issue of Toxicological Sciences ( ToxSci ), the official SOT journal, a ToxPoint article discusses “ The Importance of Conventional Toxicological Metrics of Aerosol Characterization .” This article is free to read for nonsubscribers. Other featured...
A new ToxPoint article argues that “Copper Is the New Showstopper,” while a commentary calls for patient-relevant tissue models in the September 2022 issue of Toxicological Sciences ( ToxSci ), the official journal of the Society of Toxicology (SOT). Other featured articles include a...
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